USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q9UNH7 USC-OGP 2-DE database:  Q9UNH7 Q9UNH7 General information about the entry View entry in simple text format Entry name SNX6_HUMAN Primary accession number Q9UNH7 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Sorting nexin-6; AltName: Full=TRAF4-associated factor 2; Contains: RecName: Full=Sorting nexin-6, N-terminally processed;. Gene name Name=SNX6 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0387: pI=5.73; Mw=47711 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1164: pI=5.96; Mw=49125 Cross-references UniProtKB/Swiss-Prot Q9UNH7; SNX6_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SNX6_HUMAN Primary accession number Q9UNH7 Secondary accession number(s) C0H5W9 Q9Y449 Sequence was last modified on  May 1, 2000 (version 1) Annotations were last modified on  March 15, 2017 (version 149) Name and origin of the protein Description RecName: Full=Sorting nexin-6; AltName: Full=TRAF4-associated factor 2; Contains: RecName: Full=Sorting nexin-6, N-terminally processed; Gene name Name=SNX6 Encoded on Name=SNX6 Keywords Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Endosome; Lipid-binding; Membrane; Nucleus; Phosphoprotein; Protein transport; Reference proteome; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF121856; AAD27829.1; -; mRNA EMBL U83194; AAD24202.1; ALT_INIT; mRNA EMBL AL445363; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AL445883; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471078; EAW65913.1; -; Genomic_DNA EMBL CH471078; EAW65915.1; -; Genomic_DNA EMBL BC001798; AAH01798.1; -; mRNA CCDS CCDS9648.1; -. [Q9UNH7-2]; . RefSeq NP_067072.3; NM_021249.4. [Q9UNH7-2]; . RefSeq NP_689419.2; NM_152233.3; . UniGene Hs.356647; -; . ProteinModelPortal Q9UNH7; -; . SMR Q9UNH7; -; . BioGrid 121852; 65; . DIP DIP-37549N; -; . IntAct Q9UNH7; 16; . MINT MINT-2634416; -; . STRING 9606.ENSP00000355217; -; . iPTMnet Q9UNH7; -; . PhosphoSitePlus Q9UNH7; -; . SwissPalm Q9UNH7; -; . BioMuta SNX6; -; . DMDM 10720285; -; . OGP Q9UNH7; -; . REPRODUCTION-2DPAGE IPI00298111; -; . EPD Q9UNH7; -; . PaxDb Q9UNH7; -; . PeptideAtlas Q9UNH7; -; . PRIDE Q9UNH7; -; . DNASU 58533; -; . Ensembl ENST00000396526; ENSP00000379779; ENSG00000129515. [Q9UNH7-2]; . GeneID 58533; -; . KEGG hsa:58533; -; . UCSC uc001wse.2; human. [Q9UNH7-1]; . CTD 58533; -; . GeneCards SNX6; -; . H-InvDB HIX0011592; -; . HGNC HGNC:14970; SNX6; . HPA HPA049374; -; . MIM 606098; gene; . neXtProt NX_Q9UNH7; -; . OpenTargets ENSG00000129515; -; . PharmGKB PA37946; -; . eggNOG KOG1660; Eukaryota; . eggNOG ENOG410XPZY; LUCA; . GeneTree ENSGT00870000136451; -; . HOGENOM HOG000231691; -; . HOVERGEN HBG000716; -; . InParanoid Q9UNH7; -; . KO K17920; -; . PhylomeDB Q9UNH7; -; . TreeFam TF313698; -; . SignaLink Q9UNH7; -; . ChiTaRS SNX6; human; . GenomeRNAi 58533; -; . PRO PR:Q9UNH7; -; . Proteomes UP000005640; Chromosome 14; . Bgee ENSG00000129515; -; . CleanEx HS_SNX6; -; . ExpressionAtlas Q9UNH7; baseline and differential; . Genevisible Q9UNH7; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IEA:GOC; . GO GO:0031901; C:early endosome membrane; IDA:UniProtKB; . GO GO:0019898; C:extrinsic component of membrane; IBA:GO_Central; . GO GO:0005622; C:intracellular; NAS:UniProtKB; . GO GO:0005634; C:nucleus; IEA:UniProtKB-SubCell; . GO GO:0030904; C:retromer complex; IDA:UniProtKB; . GO GO:0030905; C:retromer; tubulation complex; NAS:ParkinsonsUK-UCL GO GO:0097422; C:tubular endosome; IDA:UniProtKB; . GO GO:0034452; F:dynactin binding; IDA:UniProtKB; . GO GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central; . GO GO:0046982; F:protein heterodimerization activity; NAS:ParkinsonsUK-UCL; . GO GO:0042803; F:protein homodimerization activity; IPI:HGNC; . GO GO:0006897; P:endocytosis; IBA:GO_Central; . GO GO:0006886; P:intracellular protein transport; IMP:UniProtKB; . GO GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; NAS:UniProtKB; . GO GO:0045892; P:negative regulation of transcription; DNA-templated; IDA:UniProtKB GO GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:HGNC; . GO GO:0016241; P:regulation of macroautophagy; NAS:ParkinsonsUK-UCL; . GO GO:0042147; P:retrograde transport; endosome to Golgi; IMP:UniProtKB GO GO:0016050; P:vesicle organization; IBA:GO_Central; . Gene3D 1.20.1270.60; -; 1; . Gene3D 3.30.1520.10; -; 1; . InterPro IPR027267; AH/BAR-dom; . InterPro IPR001683; Phox; . InterPro IPR014637; SNX5/SNX6/SNX32; . InterPro IPR028657; SNX6; . InterPro IPR015404; Vps5_C; . PANTHER PTHR10555:SF185; PTHR10555:SF185; 1; . Pfam PF00787; PX; 1; . Pfam PF09325; Vps5; 1; . PIRSF PIRSF036924; Snx5_Snx6; 1; . SUPFAM SSF64268; SSF64268; 1; . PROSITE PS50195; PX; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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